Perimenopause changes the equation for women.
Estrogen shifts in your 40s change fat distribution, sleep depth, and how the body responds to insulin. Same calories, different result.
Men experience hormonal shifts too.
Testosterone trends, sleep changes, and life-load increases all matter for men in their 40s. The clinical review evaluates all of it.
Muscle mass is the leverage point.
After 40, preserving muscle becomes critical. Sustainable medical weight care typically integrates strength work alongside any medication discussion.

